Clinical Pharmacology Unit (CPU) is certified Unit working under ISO 9001, GCP and national legislation. It executes clinical trials with pharmaceuticals or medical devices (phases I., II., III. and IV.). Main interest is pharmacokinetics (PK) and pharmacodynamics (PD) of the drug and its early phase of development. In this field, CPU realizes sponsored and academic studies. Latest academic trial was to study the influence of different application drug form used in intensive care unit during nasogastric tube (NGT) applications. One of the topics on CPU is the handling and monitoring of sepsis in intensive care. Other study topics are from the field of rheumatology (Phase I), gastroenterology (Phase II), diabetology (Phase I) and oncology (Phase I). As an important step to provide IIT clinical trials, the unit prepares their own protocols. From 2019 CPU develops clinical cannabis research as a first Centre in Czech Republic. Cannabis growing and medicament production is GMP and GACP certified.