Research focus

Kardiovize team is one of FNUSA-ICRC international research teams, our mission includes data acquisition, analysis, publication, and diffusion of relevant epidemiologic and public health topics focused on cardiovascular and mental risk factors, with this knowledge are designed, implemented, and evaluated intervention programs to reduce the burden of major risk factors and are created business opportunities that contribute with the sustainability of the institution and promotion of the population health.

Research objectives

  • To assess the cardiometabolic and cognitive risk factors and their determinants in the Czech population.
  • To implement and evaluate population and individual interventions in Brno to reduce cardiovascular diseases and cognitive decline risk, as a portable model to be replicated in others cities of the region.
  • To collaborate with researchers of low and middle-income countries to improve the understanding of the complex relationship among cardiometabolic, mental, and cognitive risk factors.
  • To develop business opportunities evaluating new technologies and providing to the Brno population access to high-quality and high-technology evaluations and programs.
  • To consolidate Kardiovize as a European leading center in cardiovascular disease prevention research.

Main partners

  • Mayo Clinic, Rochester, MN, USA
  • Mount Sinai, NU, NY, USA
  • Charles University, Prague, Czech Republic

Technological equipment

  • Bioimpedance InBody 370 – measuring body composition (using bioimpedance analysis)
  • Air Displacement Plethysmograph Bod Pod - measuring body composition (using the method of AHP)

Offered services and expertise

  • Recommended methodology of community intervention programs.
  • Population-focused prevention programs, promotion of health education.
  • Enterprise-focused prevention programs.
  • Monitoring changes in awareness of the risk factors for cardiovascular disease.
  • Laboratory and diagnostic methods.

Top publications

  • GEDA, Y., ROBERTS, R., MIELKE, M., KNOPMAN, D., CHRISTIANSON, T., PANKRATZ, V., BOEVE, B., SOCHOR, O., TANGALOS, E., PETERSEN, R., ROCCA, W. Baseline Neuropsychiatric Symptoms and the Risk of Incident Mild Cognitive Impairment: A Population-Based Study. American Journal of Psychiatry. 2014, 171(5), 572-581.
  • BLUSTIN, J., MCBANE, R., MAZUR, M., AMMASH, N., SOCHOR, O., GRILL, D., WYSOKINSKI, W. The Association Between Thromboembolic Complications and Blood Group in Patients With Atrial Fibrillation. Mayo Clinic Proceedings. 2015, 90(2), 216-223.
  • PINK, A., STOKIN, GB., BARTLEY, M., ROBERTS, R., SOCHOR, O., MACHULDA, M., KRELL-ROESCH, J., KNOPMAN, S., ACOSTA, J., CHRISTIANSON, T., PANKRATZ, V., MIELKE, M., PETERSEN, R., GEDA, Y. Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: A population-based study. Neurology. 2015, 84(9), 935-943.
  • SAHAKYAN, K., SOMERS, V., RODRIGUEZ-ESCUDERO, J., HODGE, D., CARTER, R., SOCHOR, O., COUTINHO, T., JENSEN, M., ROGER, V., SINGH, P., LOPEZ-JIMENEZ, F. Normal-Weight Central Obesity: Implications for Total and Cardiovascular Mortality. Annals of Internal Medicine. 2015, 163(11), 827.
  • WOHLFAHRT, P., REDFIELD, M., MELENOVSKY, V., LOPEZ-JIMENEZ, F., RODEHEFFER, R., BORLAUG, B. Impact of chronic changes in arterial compliance and resistance on left ventricular ageing in humans. European Journal of Heart Failure. 2015, 17(1), 27-34.

Other selected results

Kardiovize 2030 patients database - Kardiovize 2030: In the project’s first phase, was assessed the prevalence of major risk factors of cardiovascular diseases (CVD) in the target population of Brno city (400 000 inhabitants), Czech Republic, performing a randomly selected sample of 2160 volunteers aged 25-64 and following the methodology of the post-MONICA study, enrolled since January 2013 till December 2014. This survey is unique in Europe combining a detailed assessment of the traditional and some novel CVD risk factors with the evaluation of health care costs and including assessment of depression, stress, cognitive tests and resting energy expenditure. Deep frozen samples of plasma, serum or isolated DNA´s in every participant open the study to other disciplines beyond cardiology in the near future.

Team members

  • Juan Pablo Gonzalez Rivas, MD
  • Jose Pantaleon Hernandez-Rodriguez, Ph.D. MBA MPH
  • Mgr. Jana Jarešová
  • Mgr. Bc. Eva Matuchová
  • Geraldo De Albuquerque Maranhao Neto, Ph.D.
  • Ing. Juraj Jakubík
  • Mgr. Monika Kunzová
  • MUDr. Šárka Kunzová, Ph.D.
  • Markéta Leščinská
  • Mgr. Dominika Mochová
  • Mgr. Iuliia Pavlovska
  • Hana Pernicová Krištofová
  • Mgr. Anna Polcrová
  • Bc. Anna Pospíšilová
  • MUDr. Robert Prosecký, MPH
  • MUDr. Mária Skladaná
  • Mgr. Martina Váňová
  • Alena Zajíčková

Principal Investigator

Juan Pablo Gonzalez Rivas, MD
Juan Pablo Gonzalez Rivas, MD
Principal Investigator
Phone: +420 54 318 5596